Abstract

Author(s): Santana Gomes, Tarcisio; Fortes Almeida, Alessandra; Hilario da Cunha Daltro, Carla; Barreto Medeiros, Jairza; Lima Gusmão Senna, Maria Helena

Introduction: Handgrip strength (HGS) is a simple and reliable method with has been suggested for the diagnosis of functional loss of muscle. However, there are few studies that associate HGS with nutritional measures in patients with chronic renal disease (CKD) in nondialysis-dependent.

Objective: To investigate the association of HGS and clinical and nutritional aspects of patients with nondialysis-dependent CKD.

Methods: This is a cross-sectional study patients performed at the Clinic of Nutrition and Nephrology of a University Hospital of reference in Bahia. We evaluated 99 patients in stages 2-4 of nondialysis-dependent CKD. FPP was evaluated in the non-dominant arm. The values obtained were compared with a national reference standard. Anthropometric, clinical, laboratory and body composition parameters were recorded.

Results: Subjects with low FPP had shorter time for CKD, phase angle, lean body mass (MCM), body cell mass (MCC), hemoglobin, and higher CRP values and older age (p < 0.05). Regardless of sex, individuals with low FPP were older (p < 0.01). No sexo feminino, pacientes com baixa força tinham menores níveis de hemoglobina, ureia e maior prevalência de diabetes mellitus (p < 0,05). As for males, the lower FPP was associated with lower body mass index (BMI), arm muscle circumference (CMB), MCM, MCC, glomerular filtration rate and phase angle (p < 0.05). The FPP correlated positively with MCC and MCM (p < 0.001).

Conclusion: The findings suggest that FPP can be used to predict loss of lean mass in patients with nondialysis-dependent CKD.