Lipodystrophy and the relationship with cardiovascular risk | 76043


Lipodystrophy and the relationship with cardiovascular risk factors and metabolic syndrome in HIV-infected patients

Author(s): Palmeira dos Santos, Tatiana Maria1; Barros da Silva, Danielle1; Monteiro Franco, Thayse1; Ribeiro dos Santos, Verônica1; De Mendonça,Jussimara2; Dos Santos Júnior, José Alfredo3; Barrozo Novais, Gabrielle4; Da Costa, Dayanne5

Introduction: HIV-positive patient lipodystrophy is the redistribution of body fat and may be accompanied by cardiovascular and metabolic disorders.

Objective: Was to investigate the prevalence of lipodystrophy in adults infected with HIV, as well as its relationship with cardiovascular risk factors and metabolic syndrome.

Methodology: Cross-sectional study with HIV-positive adult patients taking antiretroviral medication. Data were collected through a questionnaire and through medical records (viral RNA, CD4, blood glucose, LDL, HDL, triglycerides). In addition to anthropometry (waist circumference, body weight, height and BMI).

Results: 120 people studied among them (50.8%) had lipodystrophy, the highest prevalence of lipodystrophy (52.1%) occurred in males and the most widely used medication was the NRTI + PI (24,2%). The lipodystrophy was more frequent in patients with cardiovascular disease (68.4%), metabolic syndrome (59.3%) and those with increased waist circumference (55.1%). Significant differences (p <0.05) among the analyzed subgroups (with or without lipodystrophy) occurred with triglycerides, LDL and glucose levels. Discussion: The use of HAART tends to improve the condition of immunity and is associated with the onset of lipodystrophy. This also associated with excess weight and fat accumulation predisposes to the development of metabolic syndrome.

Conclusion: the study contributed to direct the focus and attention profile of specialized services for HIV/AIDS.


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Journal Highlights
  • Blood Glucose
  • Dietary Supplements
  • Cholesterol, Dehydration
  • Digestion
  • Electrolytes
  • Clinical Nutrition Studies
  • energy balance
  • Diet quality
  • Clinical Nutrition and Hospital Dietetics