Metabolic profile, anthropometric and lipodystrophy in peopl | 75853


Metabolic profile, anthropometric and lipodystrophy in people living with HIV/AIDS in antiretroviral therapy

Author(s): Conceição da Silva, Iana1; Sampaio, Ethiane1; Almeida, Maiara1; Ney Freire, Andre2; Ramos, Lílian1; Barreto Medeiros, Jairza Maria1

Introduction: The morbidity and mortality associated with HIV infection has changed in the last decades due to the evolution of antiretroviral therapy high (HAART). However, adverse effects have yet been reported with such processing. The aim of this study was to evaluate the metabolic profile, anthropometric and presence of lipodystrophy, in people living with HIV / AIDS in antiretroviral therapy, according to gender.

Methods: Corresponds to a cross-sectional study in a referral center for HIV/AIDS in the city of Salvador, Bahia, Brazil. The metabolic profile was analyzed by measurement of fasting glucose and lipid profile, anthropometric status by body mass index and waist circumference and and waist / hip ratio. The lipodystrophy was diagnosed by the technique of self-report of the patient added to confirmation health professionals. Descriptive analyzes and chi - square test were performed.

Results: The sample consisted of 80 patients, 45 (56.3 %) females, mean age 43.19 SD 7.46 years. In the study, the majority of women had central obesity and low levels of high density lipoprotein. Was identified that 75% (60) of the subjects evaluated had lipodystrophy. Among patients with lipodystrophy 53.3% (n = 32) had hypercholesterolemia (p = 0.009).Discussion: Despite advances in antiretroviral therapy is still associated with changes in lipid profile, anthropometric parameters and the presence of lipodystrophy.

Conclusion: In people living with HIV / AIDS on antiretroviral therapy, metabolic abnormalities were found, characterized by hypertriglyceridemia and low HDL levels, central obesity and lipodystrophy with differences between men and women.

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Journal Highlights
  • Blood Glucose
  • Dietary Supplements
  • Cholesterol, Dehydration
  • Digestion
  • Electrolytes
  • Clinical Nutrition Studies
  • energy balance
  • Diet quality
  • Clinical Nutrition and Hospital Dietetics