Study of body composition and metabolism and retinol binding | 76373


Study of body composition and metabolism and retinol binding protein in human immunodeficiency virus subjects from São Paulo, Brazil

Author(s): Falcoski, Carolina Agostinho1; Bim, Andréia Chiodi1; Vassimon, Helena Siqueira2; Beraldo, Rebeca Antunes1; Kutschenko, Andressa1; Ovídio, Paula Payão1; De Paula, Francisco José Albuquerque1; Jordão Junior, Alceu A.1

Objective: To evaluate body composition, metabolism and RBP, RBP4 and retinol values in HIV-patients.

Methods: Males aged between 19 and 60 were divided into two groups: infected by HIV (HIV +, n = 20) and not infected by HIV (n = 20). All subjects were submitted to X-ray absorptiometry (DXA) to assess body composition and blood samples were collected to measured retinol, RBP, RBP-4, glucose, triglycerides (TG) and high-density lipoprotein (HDL).

Results: The HIV + group showed significant lower fat mass on leg (18,5 ± 7%) than control (respectively 26 ± 6,7 %). It was observed lower levels of HDL in HIV+ group (29 ± 5 mg/dL), andhigher levels of TG (282 ± 176) than in control group (respectively 33 ± 3mg/dL, 144 ± 43 mg / dl). The ratio of TG to HDL, considered as insulin resistance parameter was higher in HIV+ group (10 ± 9) than control (4 ± 1). Neither statistical significant result was found for retinol, RBP and RBP-4.

Conclusion: HIV patients had metabolic and body composition changes, confirming lipodystrophy syndrome, but there was no difference for retinol, RBP and RBP-4 compared to control group.

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Journal Highlights
  • Blood Glucose
  • Dietary Supplements
  • Cholesterol, Dehydration
  • Digestion
  • Electrolytes
  • Clinical Nutrition Studies
  • energy balance
  • Diet quality
  • Clinical Nutrition and Hospital Dietetics